Medical Articles

Tinidazole

Anti protozoal

Description

Tinidazole is an antibiotic that is used to treat certain types of vaginal infections (bacterial vaginosis, trichomoniasis). It is also used to treat certain types of parasite infections (giardiasis, amebiasis).

Mechanism of action

Tinidazole is a prodrug and antiprotozoal agent. The nitro group of tinidazole is reduced in Trichomonas by a ferredoxin-mediated electron transport system. The free nitro radical generated as a result of this reduction is believed to be responsible for the antiprotozoal activity. It damages the DNA of bacteria and parasites and prevents them from making new DNA. By doing so, tinidazole (Tindamax) causes bacterial and parasitic cell death and stops them from growing.

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Mechanism of action

Tinidazole is a prodrug and antiprotozoal agent. The nitro group of tinidazole is reduced in Trichomonas by a ferredoxin-mediated electron transport system. The free nitro radical generated as a result of this reduction is believed to be responsible for the antiprotozoal activity. It damages the DNA of bacteria and parasites and prevents them from making new DNA. By doing so, tinidazole (Tindamax) causes bacterial and parasitic cell death and stops them from growing.

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