Medical Articles

Sulphadiazine + Trimethoprim

Antibiotics

Description

used to treat certain infections such as bladder and prostate infections, Nocardia infections, or parasitic infections.

Mechanism of action

The drugs exert their action on two step enzymatic pathway for tetrahydrofolic acid synthesis. Sulphamethoxazole inhibits PABA incorporation into folic acid; trimethoprim inhibits reduction of dihydrofolate to tetrahydrofolate.

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Mechanism of action

The drugs exert their action on two step enzymatic pathway for tetrahydrofolic acid synthesis. Sulphamethoxazole inhibits PABA incorporation into folic acid; trimethoprim inhibits reduction of dihydrofolate to tetrahydrofolate.

This page is restricted. Please Login / Register to view this page.