Medical Articles

Selegiline

Drugs used in parkinsonism and other movement disorders

Description

Selegiline, a monoamine oxidase (MAO) inhibitor, is approved by the U.S. Food and Drug Administration (FDA) as an adjunct treatment for patients with Parkinson disease and a major depressive disorder in adults.

Mechanism of action

The action occurs as the drug potentiates the effect of levodopa by decreasing the metabolism of dopamine. It is an inhibitor of monoamine oxidase enzyme (MAO-B) in brain.

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Mechanism of action

The action occurs as the drug potentiates the effect of levodopa by decreasing the metabolism of dopamine. It is an inhibitor of monoamine oxidase enzyme (MAO-B) in brain.

This page is restricted. Please Login / Register to view this page.