Mechanism of action
It is an enzyme used along with HCl in gastric achylia due to atrophic gastritis, Gastric carcinoma, and pernicious anaemia.
Pepsin is a stomach enzyme that serves to digest proteins found in ingested food. Gastric chief cells secrete pepsin as an inactive zymogen called pepsinogen. Parietal cells within the stomach lining secrete hydrochloric acid that lowers the pH of the stomach. A low pH (1.5 to 2) activates pepsin
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