Mechanism of action
In anaerobic microorganisms metronidazole is converted to active form by reduction of its nitro group this gets bound to DNA and prevents nucleic acid formation.
Medical Articles
Ornidazole is a C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 3-chloro-2-hydroxypropyl and methyl groups, respectively. It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections.
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