Mechanism of action
Nortriptyline inhibits the activity of histamine, 5 – HT and acetylcholine. It interferences with transport, release and storage of catecholamine.
Medical Articles
Nortriptyline is indicated for use in the treatment of depression (FDA-approved). It can also be used off-label for conditions such as chronic pain, diabetic neuropathy, myofascial pain, orofacial pain, and postherpetic neuralgia. Nortriptyline has also shown to be useful in patients trying to quit smoking.
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