Mesna (sodium 2-mercaptoethane sulfonate) is a detoxifying medicine used to prevent hemorrhagic cystitis in patients receiving chemotherapy with either high-dose cyclophosphamide or ifosfamide.
What is the mechanism of action? Mesna binds to and inactivates the substances from ifosfamide that cause irritation to the lining of the bladder and bleeding. By inactivating these substances, hemorrhagic cystitis is reduced or prevented.
What is the mechanism of action? Mesna binds to and inactivates the substances from ifosfamide that cause irritation to the lining of the bladder and bleeding. By inactivating these substances, hemorrhagic cystitis is reduced or prevented.
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