Mechanism of action
Mebeverine is an antispasmodic agent that works directly on intestinal smooth muscles and may also have a local anaesthetic effect and weak atropine-like activity. Mebeverine is an anticholinergic but its mechanism of action is not known; it appears to work directly on smooth muscle within the gastrointestinal tract and may have an anaesthetic effect, may affect calcium channels, and may affect muscarinic receptors. It is metabolized mostly by esterases, and almost completely.