Medical Articles

Mebendazole

Anti helminthic

Description

Mebendazole is used to treat infections caused by worms. It works by keeping the worm from absorbing sugar (glucose), so that the worm loses energy and dies.Mebendazole is used to treat pinworm, whipworm, roundworm, and hookworm infections.

Mechanism of action

Mebendazole acts by inhibiting the production of microtubules via binding to colchicine binding-site of β-tubulin and thereby blocking polymerization of tubulin dimers in the intestinal cells of parasites, which eventually lead parasites to be in shortage of glycogen.

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Mechanism of action

Mebendazole acts by inhibiting the production of microtubules via binding to colchicine binding-site of β-tubulin and thereby blocking polymerization of tubulin dimers in the intestinal cells of parasites, which eventually lead parasites to be in shortage of glycogen.

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