Mechanism of action
The site of action is proximal tubule and loop of Henle, where it prevents the rebsorption of water and also by complex mechanisms, of sodium. This leads to increase in urine volume.
Mannitol 20% Infusion is a medicine used in the treatment of acute renal (kidney) failure, cerebral edema (accumulation of excessive fluid in the brain) and to reduce the pressure inside the eyes in a condition called glaucoma. IT is a clear and colorless solution of 20 grams of mannitol, USP per 100 mL (0.2 grams/mL)…
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