Mechanism of action
Non-selective dual antagonism of ETA and ETB endothelin receptors on pulmonary vascular smooth muscle and endothelium, reducing pulmonary vasoconstriction and disease progression.
Medical Articles
Dual ERA for pulmonary arterial hypertension (PAH). Reduces pulmonary vascular resistance and right ventricular afterload by blocking both endothelin receptors.
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© 2025 The Doctors Platform. All Right Reserved.