Mechanism of action
It blocks both open and inactivated cardiac sodium channels. It also decreases automaticity by reducing the slope of phase 4 and altering threshold for excitability.
Medical Articles
Lidocaine is a local anesthetic agent commonly used for local and topic anesthesia, but it also has antiarrhythmic, and analgesic uses and can be used as an adjunct to tracheal intubation. It is a tertiary amine and is a class Ib antiarrhythmic agent on the Vaughan-Williams classification.
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