Medical Articles

Iron III Hydroxide Polymaltose Complex (IPC)

Hematinics & haematopoietic

Description

Iron(III)-hydroxide polymaltose complex (IPC) is an iron preparation with non-ionic iron and polymaltose in a stable complex.

Mechanism of action

The absorption of ferric iron from IPC is controlled by a feedback mechanism. When IPC comes in contact with the iron binding sites at the mucosal surface, a physiological exchange is assumed to occur. IPC releases the required amount of ferric iron, which is actively transported into the mucosal cell by a carrier protein and from there released for binding to ferritin or transferrin.

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Mechanism of action

The absorption of ferric iron from IPC is controlled by a feedback mechanism. When IPC comes in contact with the iron binding sites at the mucosal surface, a physiological exchange is assumed to occur. IPC releases the required amount of ferric iron, which is actively transported into the mucosal cell by a carrier protein and from there released for binding to ferritin or transferrin.

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