Tricyclic antidepressants are the most commonly used drugs. They produce anti depressant effect by blocking the neuronal uptake of noradrenaline and exert anticholinergic activity. They also inhibit neuronal uptake of 5HT and dopamine. The exact mechanism of action is not known. The anti depressant effect is noticed after 3-4 weeks.
Tricyclic antidepressants are the most commonly used drugs. They produce anti depressant effect by blocking the neuronal uptake of noradrenaline and exert anticholinergic activity. They also inhibit neuronal uptake of 5HT and dopamine. The exact mechanism of action is not known. The anti depressant effect is noticed after 3-4 weeks.
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