Mechanism of action
Acts on feeding centers in CNS and inhibits it, and thereby suppresses appetite.
Medical Articles
Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures.The action of fenfluramine that reduces the appetite is mediated by its interaction with the metabolism of serotonin—5-hydroxytryptamine (5-HT)—in the brain.
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