Dulaglutide injection is used to treat type 2 diabetes mellitus. Dulaglutide is used together with diet and exercise to help control your blood sugar. This medicine also lowers the risk of death, heart attack, or stroke in patients with diabetes and heart or blood vessel problems.
Dulaglutide is an analogue of glucagon-like peptide-1 (GLP-1), an incretin hormone linked to a modified human Ig G4 fragment and act as GLP-1 receptor agonist. Activation of GLP-1 stimulates insulin release by increasing intracellular cyclic AMP (cAMP) in pancreatic beta cells and suppression of glucagon secretion in a glucose-dependent manner. It also slows gastric emptying thus reduces postprandial glucose (PPG) concentration.
Dulaglutide is an analogue of glucagon-like peptide-1 (GLP-1), an incretin hormone linked to a modified human Ig G4 fragment and act as GLP-1 receptor agonist. Activation of GLP-1 stimulates insulin release by increasing intracellular cyclic AMP (cAMP) in pancreatic beta cells and suppression of glucagon secretion in a glucose-dependent manner. It also slows gastric emptying thus reduces postprandial glucose (PPG) concentration.
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