Medical Articles

Dithranol

Drugs used for psoriasis

Description

Anthralin or dithranol (Dithrocream, Micanol, Psorlin) is a hydroxyanthrone (anthracene derivative) medicine applied to the skin of people with psoriasis. It is available as creams, ointment, or pastes in 0.1 to 2% stengths. This substance has been used to treat psoriasis for more than 100 years.

Mechanism of action

A topical agent that binds DNA, inhibiting synthesis of nucleic protein, and reduces mitotic activity. Therapeutic Effect: Results in damage to DNA sugar and enhances membrane lipid peroxidation, which may play a critical role in the antipsoriatic action.

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Mechanism of action

A topical agent that binds DNA, inhibiting synthesis of nucleic protein, and reduces mitotic activity. Therapeutic Effect: Results in damage to DNA sugar and enhances membrane lipid peroxidation, which may play a critical role in the antipsoriatic action.

This page is restricted. Please Login / Register to view this page.