Medical Articles

Digoxin

Drugs used in cardiac failure & shock

Description

Digoxin is a medication used to manage and treat heart failure and certain arrhythmias, and abortion. It is in the cardiac glycoside class of drugs ,used to improve the strength and efficiency of the heart, or to control the rate and rhythm of the heartbeat. This leads to better blood circulation and reduced swelling of…

Mechanism of action

The main action of digoxin is its direct effect on heart to increase the force of myocardial contraction. The beneficial effects of digoxin in patients of heart failure are explained on the basis of +ve inotropic action. It also has direct -ve chronotropic effect. In patients of heart failure after digoxin administration there is decreased heart size, venous pressure and blood volume. Diuresis occurs and there is relief of oedema.

 

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Mechanism of action

The main action of digoxin is its direct effect on heart to increase the force of myocardial contraction. The beneficial effects of digoxin in patients of heart failure are explained on the basis of +ve inotropic action. It also has direct -ve chronotropic effect. In patients of heart failure after digoxin administration there is decreased heart size, venous pressure and blood volume. Diuresis occurs and there is relief of oedema.

 

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