Medical Articles

Di-iodohydroxyquinoline

Anti protozoal

Description

Diiodohydroxyquinoline (5,7-diiodo-8-hydroxyquinoline) is a fine pale yellow powder containing 63.9 per cent of iodine which is used orally in the treatment of amebiasis and other protozoal intestinal infections and vaginally (in the preparation floraquin®) in the treatment of trichomonas infection.

Mechanism of action

Di-iodohydroxyquinoline is directly amoebicidal. It has activity against motile and cystic forms. Shows activity against amoebae in intestinal tract, but is ineffective in extraintestinal amoebiasis. It is also effective in cyst passing patients.

 

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Mechanism of action

Di-iodohydroxyquinoline is directly amoebicidal. It has activity against motile and cystic forms. Shows activity against amoebae in intestinal tract, but is ineffective in extraintestinal amoebiasis. It is also effective in cyst passing patients.

 

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