Mechanism of action
It activates the 5-HT (serotonin) 2C receptor. Serotonin is a neurotransmitter involved in regulation of fat storage and many other biological processes. Serotonin binds to several different receptors with related but distinct biological effects. Dexfenfluramine causes weight loss by suppressing appetite through alterations in serotonin levels in the brain. Weight loss is maintained only as long as the individual keeps taking the drug.