Medical Articles

Datteparin Sodium

Anti coagulants

Mechanism of action

The antithrombotic effect of dalteparin sodium is dependent on its ability to potentiate the inhibition of factor Xa and thrombin by antithrombin {AT}. It has a relatively higher ability to potentiate factor Xa inhibition than to prolong plasma clotting time {APTT}. It has a smaller effect on platelet function and platelet adhesion than heparin, and thus has only a small effect on primary homeostasis.
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Mechanism of action

The antithrombotic effect of dalteparin sodium is dependent on its ability to potentiate the inhibition of factor Xa and thrombin by antithrombin {AT}. It has a relatively higher ability to potentiate factor Xa inhibition than to prolong plasma clotting time {APTT}. It has a smaller effect on platelet function and platelet adhesion than heparin, and thus has only a small effect on primary homeostasis.
This page is restricted. Please Login / Register to view this page.