Mechanism of action
Stimulates presynaptic, alpha 2 receptors in
vasomotor centre of brain causing decreased sympathetic outflow which
results in fall of blood pressure.
Clonidine is an antihypertensive drug that lowers blood pressure and heart rate by relaxing the arteries and increasing the blood supply to the heart; it has the following FDA-approved indications: Hypertension, as mentioned above; pediatric use for hypertension is off-label.
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