Chlorthalidone is a medication used in the management and treatment of hypertension. It is in the thiazide-like diuretics class of drugs. This activity reviews chlorthalidone's indications, action, and contraindications as a valuable agent in managing hypertension, edema, and calcium nephrolithiasis.
The primary site of action of thiazide diuretics is the distal convoluted tubule. At this site, inhibition of NaCl transport
is caused, leading to diuresis. Thiazide diuretics inhibit the Na+Cl- transport, perhaps by competing for the Cl- binding site.
The primary site of action of thiazide diuretics is the distal convoluted tubule. At this site, inhibition of NaCl transport
is caused, leading to diuresis. Thiazide diuretics inhibit the Na+Cl- transport, perhaps by competing for the Cl- binding site.
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© 2025 The Doctors Platform. All Right Reserved.
