Medical Articles

Chlorpromazine

Sedatives - Hypnotics

Description

It is a first generation antipsychotic also falls in neuroleptic drug category and is used to manage and treat schizophrenia, bipolar disorder and acute psychosis.

Mechanism of action

Postulated that it blocks dopamine receptors in CNS. Other pharmacological actions seen in varying degrees include cholinergic, adrenergic, histaminergic and serotonergic blocking activity. The exact mechanism of its action is unknown. When administered to normal person it causes emotional quietening, indifference to surroundings and sedation. When given in psychotics it decreases agitation, aggressiveness and tend to bring behaviour towards normality. Its administration may cause movement disorders.

 

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Mechanism of action

Postulated that it blocks dopamine receptors in CNS. Other pharmacological actions seen in varying degrees include cholinergic, adrenergic, histaminergic and serotonergic blocking activity. The exact mechanism of its action is unknown. When administered to normal person it causes emotional quietening, indifference to surroundings and sedation. When given in psychotics it decreases agitation, aggressiveness and tend to bring behaviour towards normality. Its administration may cause movement disorders.

 

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