Medical Articles

Cefepime and enmetazobactam

Cephalosporin/beta-lactamase inhibitor combination

Description

First cefepime combination approved for complicated UTI and pyelonephritis caused by ESBL-producing Enterobacteriaceae.

Mechanism of action

Cefepime: 4th generation cephalosporin inhibits bacterial cell wall synthesis. Enmetazobactam: novel beta-lactamase inhibitor effective against ESBLs, protecting cefepime from hydrolysis.

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Mechanism of action

Cefepime: 4th generation cephalosporin inhibits bacterial cell wall synthesis. Enmetazobactam: novel beta-lactamase inhibitor effective against ESBLs, protecting cefepime from hydrolysis.

This page is restricted. Please Login / Register to view this page.