Medical Articles

Calcitriol

Drugs used in osteoporosis acting on bone metabolism

Description

Calcitriol is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis.iIt s als used to treat plaque psoriasis, a skin problem where your body produces too many skin cells, causing patches of dry, itchy, scaly skin (plaques).

Mechanism of action

It stimulates the vitamin D receptor in the intestine, kidneys, parathyroid gland and bone to promote Ca transport and absorption thus increasing serum Ca levels. It also stimulates bone resorption and renal tubular reabsorption of Ca thereby decreasing parathyroid hormone (PTH) levels and maintaining Ca-phosphate homeostasis.

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Mechanism of action

It stimulates the vitamin D receptor in the intestine, kidneys, parathyroid gland and bone to promote Ca transport and absorption thus increasing serum Ca levels. It also stimulates bone resorption and renal tubular reabsorption of Ca thereby decreasing parathyroid hormone (PTH) levels and maintaining Ca-phosphate homeostasis.

This page is restricted. Please Login / Register to view this page.