A neuromuscular blocking agent widely used in anesthesia
It is a competitive antagonist of acetylcholine at neuromuscular junction and cause flaccid paralysis of skeletal muscles. The neuromuscular block of this type can be reversed by administration of anticholinesterase drug (neostigmine) which inhibits the enzyme cholinesterase so that acetylcholine is not degraded. Hence the concentration of acetylcholine increases which tends to decrease the effect of neuromuscular blocker.
It is a competitive antagonist of acetylcholine at neuromuscular junction and cause flaccid paralysis of skeletal muscles. The neuromuscular block of this type can be reversed by administration of anticholinesterase drug (neostigmine) which inhibits the enzyme cholinesterase so that acetylcholine is not degraded. Hence the concentration of acetylcholine increases which tends to decrease the effect of neuromuscular blocker.
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