What is PAS in TB treatment?
Para-aminosalicylic acid (PAS) is a second-line anti-TB drug (SLD) that was found to be effective for treatment of TB in the 1940s. As a structural analog of p-aminobenzoic acid, it disrupts folate metabolism through competitive binding with dihydrofolate reductase, thereby inhibiting the growth of tubercle bacilli.
Para-aminosalicylic acid (PAS) is a second-line anti-TB drug (SLD) that was found to be effective for treatment of TB in the 1940s. As a structural analog of p-aminobenzoic acid, it disrupts folate metabolism through competitive binding with dihydrofolate reductase, thereby inhibiting the growth of tubercle bacilli.
© 2025[current_year] The Doctors Platform. All Right Reserved.
© 2025 The Doctors Platform. All Right Reserved.
