Medical Articles

Mupirocin

Anti septics (local)

Description

Mupirocin topical cream is used to treat secondarily infected traumatic skin lesions due to specific bacteria. Mupirocin topical ointment is used to treat impetigo. This medicine works by killing bacteria or preventing their growth.

Mechanism of action

It exerts its action on bacteria by acting as a competitive inhibitor of enzyme isoleucyl transfer RNA synthetase and competes with amino acid isoleucine for enzyme binding sites. This enzyme reaction is necessary for the incorporation of isoleucine in the protein chain. Hence it inhibits protein synthesis.

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Mechanism of action

It exerts its action on bacteria by acting as a competitive inhibitor of enzyme isoleucyl transfer RNA synthetase and competes with amino acid isoleucine for enzyme binding sites. This enzyme reaction is necessary for the incorporation of isoleucine in the protein chain. Hence it inhibits protein synthesis.

This page is restricted. Please Login / Register to view this page.