Mechanism of action
LMWH exerts its action mostly by antithrombin mediated inhibition of factor Xa. But some thrombin inhibition by LMWH is retained and is of importance for the antithrombotic effect.
Low-molecular-weight heparins (LMWHs) are a new class of anticoagulants derived from unfractionated heparin (UFH). They have a number of advantages over UFH that have led to their increasing use for a number of thromboembolic indications.
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