Medical Articles

Fosfomycin

Phosphonic antibiotic (Pyruvic acid analog)

Description

Broad-spectrum bactericidal antibiotic effective against Gram-positive, Gram-negative bacteria including multidrug-resistant strains and ESBL producers. Unique single-dose oral regimen for uncomplicated UTIs.

Mechanism of action

Inhibits bacterial cell wall synthesis by inactivating pyruvyl transferase (MurA), blocking the first committed step in peptidoglycan biosynthesis. Bactericidal action independent of bacterial cell division.

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Mechanism of action

Inhibits bacterial cell wall synthesis by inactivating pyruvyl transferase (MurA), blocking the first committed step in peptidoglycan biosynthesis. Bactericidal action independent of bacterial cell division.

This page is restricted. Please Login / Register to view this page.