Medical Articles

Quviviq (Daridorexant)

Dual orexin receptor antagonist (DORA) - Hypnotic

Description

Selective dual orexin receptor antagonist approved for insomnia characterized by difficulty with sleep onset and/or sleep maintenance. Daridorexant (formerly nemorexant) reduces wakefulness during sleep by blocking orexin signaling.

Mechanism of action

Selective antagonism of both orexin-1 and orexin-2 receptors in the brain. Blocks orexin neuropeptide signaling, which maintains wakefulness, thereby promoting sleep onset and maintenance. More selective than traditional sedative-hypnotics.

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Mechanism of action

Selective antagonism of both orexin-1 and orexin-2 receptors in the brain. Blocks orexin neuropeptide signaling, which maintains wakefulness, thereby promoting sleep onset and maintenance. More selective than traditional sedative-hypnotics.

This page is restricted. Please Login / Register to view this page.